Shiga Toxin-Producing Escherichia coli Can Impair T84 Cell Structure and Function without Inducing Attaching/Effacing Lesions

Shiga toxin-producing Escherichia coli can impair T84 cell structure and function without inducing attaching/effacing lesions.

Enteropathogenic Escherichia coli (EPEC) intimately adhere to epithelial cells producing cytoskeletal rearrangement with typical attaching and effacing lesions and altered epithelial barrier and transport function. Since EPEC and Shiga toxin-producing E. coli (STEC) share similar genes in the "locus for enterocyte effacement" (LEE) thought to cause these changes, it has been assumed that STEC s...

Shiga toxin-producing Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) cause hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS) in humans. Outbreaks are linked to bovine food sources. STEC O157:H7 has been responsible for the most severe outbreaks worldwide. However, non-O157 serotypes have emerged as important enteric pathogens in several countries. The main virulence factor of STEC is the production of Shig...

Shiga Toxin – producing Escherichia coli

1. Rautio M, Lonnroth M, Saxen H, Nikku R, Väisanen ML, Finegold SM, et al. Characteristics of an unusual anaerobic pigmented gram-negative rod isolated from normal and infl amed appendices. Clin Infect Dis. 1997;25(Suppl 2):S107–10. 2. Rautio M, Saxen H, Siitonen A, Nikku R, Jousimies-Somer H. Bacteriology of histopathologically defi ned appendicitis in children. Pediatr Infect Dis J. 2000;19:...

Shiga Toxin Producing Escherichia coli

Shiga Toxin–producing Escherichia coli, Idaho

1. Rautio M, Lonnroth M, Saxen H, Nikku R, Väisanen ML, Finegold SM, et al. Characteristics of an unusual anaerobic pigmented gram-negative rod isolated from normal and infl amed appendices. Clin Infect Dis. 1997;25(Suppl 2):S107–10. 2. Rautio M, Saxen H, Siitonen A, Nikku R, Jousimies-Somer H. Bacteriology of histopathologically defi ned appendicitis in children. Pediatr Infect Dis J. 2000;19:...